08
02 2023
Recently, a research team led by Prof. CONG Zhiqi from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) has developed new engineering Cytochrome P450BM3 enzymes for direct nitration of unsaturated hydrocarbons.
Biocatalytic nitration is a promising method for the preparation of nitro compounds. However, few nitration reactions have been developed using biocatalysis due to the lack of native nitrating enzymes and/or the narrow substrate scope of the ...
23
12 2022
Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) have proposed a new technology, called the Optical tweezer-assisted pool-screening and single-cell isolation (OPSI) system, has achieved 99.7% purity of sorting target cells, all done in real-time. Current cell-sorting methods cannot effectively sort cells of various sizes while maintaining their viability for future testing, which can be problematic when studying cancer cells or pathogenic bacteria.
Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) have proposed a new technology, called the Optical tweezer-assisted pool-screening and single-cell isolation (OPSI...
13
12 2022
Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) and their collaborators have proposed a new system called "EasySort AUTO" that allows single-cell analysis even of bacteria. It is based on artificial intelligence image recognition.
The identification, sorting and export of single bacterial cells rather than just populations of them has long been incredibly complex, expensive and often just does not work without damaging the cells.
Now, researchers from the Qingdao I...
09
11 2022
Recently, researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) identified a protein complex, named MAC, required for DNA damage response in plants. This work was published in Plant Physiology on Nov. 04.
In animals, DNA damage could lead to cancers. Although plants live for a long time without cancers, their growth is always challenged by many environmental factors, such as radiation, salinity, heavy metals and flooding, which can lead to DNA...
30
11 2022
Recently, a research team led by Prof. CONG Zhiqi from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) has developed a new “ synergistic using protein engineering and exogenous molecules” approach to achieve multi-site highly regio- and enantioselective hydroxylation of alkylbenzenes. Direct selective hydroxylation, one of the most convenient and economical routes employed in C-H oxyfunctionalization has been widely utilized in various of fields, including medicine, chemical industry, materials science, and so on. Despite remar...
02
11 2022
A new method to find and harvest cells from the environment by screening the cells first and then culturing them was proposed in a paper published in ISME Communications on Oct. 31. They use a technique called single-cell Raman-activated sorting and cultivation.
Currently, the best way for scientists to isolate a specific microbe with a particular metabolic function from an environment is to take a sample of cells, culture them, and then screen them for the desired cell functions.
This method has...
