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Research Progress
  • 27

    03 2024

    From monooxygenases to peroxizymes: recent progress in enzyme engineering of cytochrome P450s

    Recently, a team led by Prof. Zhiqi Cong from the Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences was invited to summarize its progress in transformation of natural NAD(P)H-dependent P450 monooxygenases into their peroxizyme modes, providing an alternative approach to improve the practical catalytic potential of P450 in vitro.
      Cytochrome P450 monooxygenase is a versatile oxidizing enzyme with great potential in synthetic chemistry and biology.
      Recently, a team led by Prof. Zhiqi Cong from the Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chin...

  • 27

    03 2024

    Researchers Reveal Structure and Assembly Mechanism of Unique Module in Cellulosome

    Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) have characterized the structure and assembly mode of a unique cellulosomal assembly module, the double-dockerin module, revealing the intricate complexity and diversity of cellulosome assembly and regulation.
      Cellulosomes are multi-enzyme complexes known for their efficient lignocellulose degradation, which is valuable in bioenergy technique development. The diverse composition and intricate assembly of cellulosomes give them exceptional substrate...

  • 27

    03 2024

    Module Regulating Culm Development Changes Architecture and Improves Biomass of Switchgrass

    Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) have clarified the mechanism that miR156-SPL-CKX4 module regulates cytokinin homeostasis and then affects culm development in switchgrass. Based on this, novel switchgrass germplasm that exhibits greater tiller numbers and thicker culm can be obtained by the precise manipulation of the downstream gene PvCKX4.
      Tiller number per plant and the average weight per tiller are two key factors contributing to biomass production in switchgrass and other grass species. However, the excessive grass tiller number always has a negative impact on culm developme...

  • 21

    03 2024

    The Qingdao Institute of Bioenergy and Bioprocess Technology has recently published an important review in engineering Clostridium autoethanogenum to synthesize the biochemicals and biocommodities

    Qingdao C1 refinery engineering research center, QingDao institute of bioenergy and bioprocess technology has published a review article, which summarized and prospected the metabolic engineering of self-produced ethanol Clostridia for the synthesis of chemicals and biocommodities from syngas.
      The transition to fossil fuel utilization has led to serious environmental consequences, exacerbating global warming and bringing further climate change. In the face of these challenges, multiple approaches are needed to develop alternative s...

  • 21

    03 2024

    The Qingdao Institute of Bioenergy and Bioprocess Technology has recently published an important review in the field of anaerobic bacteria synthetic biology

    Qingdao C1 refinery engineering research center, QingDao institute of bioenergy and bioprocess technology has focused on the development of genetic editing tools for gut anaerobic bacteria, including Bacteroides spp. and Clostridium spp.
      Anaerobic microorganisms play crucial roles in human health and microbial green manufacturing. Although techniques such as 16S rRNA analysis and multi-omics approaches have been widely used to study the association between microbial metabolit...

  • 21

    03 2024

    Researchers Achieve Highly Efficient Heterogeneous Telomerization of 1,3-butadiene with Methanol

    Recently, based on the Scholl reaction, a kind of low-surface-area carbene functionalized hypercrosslinked polymers was developed by Yong Yang’s low-carbon catalytic conversion research group at Catalytic Polymerization and Process Research Center of Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences.
      To promote the high-quality development of high-end polyolefin, the development of highly efficient heterogeneous catalysts for the telomerization of 1,3-butadiene and methanol to the linear product (1-methoxy-2,7-octadiene, 1-MOD) has receiv...