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Research Progress
  • 28

    04 2026

    Scientists Identify Molecular Switch That Coordinates Yeast Metabolism

    Researchers at the Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences discovered that the E3 ubiquitin ligase PTR1 coordinates carotenoid, sterol, and lipid metabolism in yeast. PTR1 forms a regulatory network with the White Collar Complex and interacting proteins, balancing biosynthetic flux. Conserved across eukaryotes, PTR1-mediated ubiquitination represents a general mechanism for metabolic regulation. These findings expand E3 ligase functions beyond protein turnover and offer new strategies for optimizing microbial production of astaxanthin, sterols, and lipids. Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences (CAS), have identified a conserved ubiquitin-mediated regulatory mechanism that coordinates metabolic flux among multiple biosynthetic pathw...

  • 23

    04 2026

    New Process Ramanomics Platform Enables Real-Time, Single-Cell Monitoring of Industrial Fermentation

    Scientists from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences, in collaboration with Tsinghua University, the Chinese Academy of Agricultural Sciences, Beijing PhaBuilder Biotechnology Co., Ltd., and Qingdao Single-Cell Biotech Co., Ltd., have developed a “process ramanomics” platform that transforms industrial fermentation tanks from opaque “black boxes” into transparent, data-rich environments. A collaborative research team led by the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences has developed a new "process ramanomics" platform. This technology transforms industrial fermentation tan...

  • 16

    04 2026

    A single-file molecular highway: Mimicking biological channels to extract heavy metals

    That is essentially the challenge of separating critical heavy metals like uranium, copper, and gold from complex industrial liquids, where they are mixed with highly similar competing ions. Imagine an exclusive event where the invited VIPs and the party-crashers look virtually identical, wearing the exact same outfits and standing at the exact same height. How do you instantly let the true VIPs through while blocking the imposters? T...

  • 02

    04 2026

    New Multi-Feature Single-Cell Platform Speeds Up Antifungal Susceptibility Testing

    The study, published on March 27 in the journal of Analytical Chemistry, introduces a multifeature antifungal susceptibility testing platform (MAFST), designed to address a longstanding challenge in clinical mycology: current susceptibility tests are often too slow, labor-intensive, or inconsistent across fungal species and drug classes. According to a new study published in Analytical Chemistry on March 27, Chinese scientists have developed a rapid and broadly applicable platform for antifungal susceptibility testing, offering a potential new route to faster and more informative ...

  • 17

    03 2026

    Scientists Develop Magnetic Bead-Based System for High-Fidelity DNA Synthesis

    Scientists from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) and the Tianjin Institute of Industrial Biotechnology (TIB), both part of the Chinese Academy of Sciences, have introduced a rapid, high-throughput error-correction platform designed to improve the accuracy of synthetic DNA. Scientists from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) and the Tianjin Institute of Industrial Biotechnology (TIB) of CAS, have developed a rapid, high-throughput error-correc...

  • 17

    03 2026

    Scientists Map Single-Cell Metabolic Interactions Across Coral–Symbiodiniaceae–Bacterial Holobiont

    Researchers from Hainan University, in collaboration with the Qingdao Institute of Bioenergy and Bioprocess Technology of the Chinese Academy of Sciences (CAS), established a single-cell, in-situ metabolite-detection workflow for coral. The platform sheds light on carbon and nitrogen transfer and recycling across the coral–Symbiodiniaceae–bacteria consortium, producing a first single-cell in-situ metabolic atlas of the coral holobiont. Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) and Hainan University have developed a workflow for detecting metabolites in single cells of corals in situ. This new p...