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Research Progress
  • 06

    11 2023

    Structurally Editable Proximal Cofactor-like Module Helps to Construct Artificial Dual-center Peroxygenase

    A new study led by Prof. CONG Zhiqi from Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) has developed an unprecedented approach for assembling artificial metalloenzymes and substantially increases the catalytic promiscuity of P450 enzymes. Cytochrome P450 monooxygenases are widely involved in the synthesis and metabolism of endogenous and exogenous substances in living organisms. The catalytic efficiency of cytochrome P450 monooxygenase relies on the coenzyme NAD(P)H and reducing ch...

  • 27

    10 2023

    Newly Discovered Bacterial Transcription Mechanism May Inform Synthetic Biology Engineering

    Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) have discovered that the SigI are more distinct than previously understood — so much so that they require an entirely new classification group. Their findings, published in Nature Communications on Oct. 13, may help inform the design of gene regulation tools. Bacterial transcription is a production line of copying over genetic instructions from double stranded DNA to produce RNA, which is then used for the subsequent production of proteins that the bacterium needs at that moment. The line supervisors a...

  • 24

    10 2023

    Iodine Improves lithium Thionyl Chloride Battery Discharge Performance and Rechargeability

    Lithium thionyl chloride (Li-SOCl2) batteries use a liquid thionyl chloride (SOCl2) electrolyte to give the battery superior energy density and stability, long life and low levels of energy loss during storage. Despite these advantages, Li-SOCl2 batteries can only be used in devices requiring low rates of energy discharge and cannot be recharged. Incorporating molecular iodine (I2) into the SOCl2 battery electrolyte not only increases the rate of energy discharge but also allows the battery to be efficiently recharged, increasing the practicality of Li-SOCl2 batteries for routine energy storage. Lithium thionyl chloride (Li-SOCl2) batteries use a liquid thionyl chloride (SOCl2) electrolyte to give the battery superior energy density and stability, long life and low levels of energy loss during storage.
      Despite these advantages, Li-SOC...

  • 09

    10 2023

    Salt-Concentrated Hydrogel Electrolytes for Long-Life Rechargeable Batteries

    Recently, researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) have developed an unconventionally salt-concentrated hydrogel electrolyte reaching a salt fraction up to 44 mol% without phase separation, which essentially suppresses water-induced side reactions and thus enables practical long-cycling operation of aqueous sodium-ion batteries. Hydrogel electrolytes are promising in developing flexible and safe batteries, but the presence of large amounts of free solvent water makes battery chemistries constrained by parasitic H2 evolution and electrode dissolution.
      Recently, researc...

  • 25

    09 2023

    BSI-AST chip:A Powerful Tool to Accelerate Antimicrobial Susceptibility Testing for Bloodstream Infections

    Researchers from Shandong University, Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) and the Affiliated Hospital of Qingdao University have developed an integrated microfluidic chip (BSI-AST chip) for rapid AST from positive blood cultures (PBCs) and the whole process from bacteria extraction to AST result output was less than 3.5 hours. It promises to be a powerful new tool for accelerating AST for bloodstream infections. The presence of viable bacteria in the blood, i.e., bacteremia, when not controlled properly can lead to bloodstream infection (BSI) and sepsis, a syndromic inflammatory response.
      Rapid and accurate antimicrobial prescriptions are critical to ...

  • 25

    09 2023

    Scientists Ddesign Lliquid Mmetal-based Sself-oscillating Bbimorph Ffilms for Ppersistent Eenergy-harvest from Mmoisture

    A research group led by Prof. LI Chaoxu from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT), Chinese Academy of Sciences (CAS), has revealed that liquid metal-based self-oscillating bimorph films may promise the persistent energy-harvest from moisture via electromagnetic induction. With the miniaturization of electronic devices and their integration within human wearable accessories, harvesting tiny energy from the ambient environment for supplying these low-energy and wearable electronics has drawn huge research interest an...