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Research Progress
  • 05

    12 2023

    Cracking 6mA Code to Enhance Lipid Accumulation in Microalgae

    A new study led by Prof. XU jian from Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT), Chinese Academy of Sciences (CAS) has unraveled the distribution pattern and dynamic changes of N6-methyladenosine (6mA) at a single-cell resolution in wild-type and 6mA-disrupted mutant strains, revealing its crucial role in lipid accumulation, especially under high light conditions. Microalgae—which are major contributors to global photosynthesis and primary productivity—serve as promising chassis cells in synthetic biology.
      In a study published in Plant Communications, researchers from the Qingdao Institute of Bioenerg...

  • 06

    11 2023

    High-throughput Mass Spectrometry Platform Enables In-situ Screening of Fatty Acid-producing Strains

    Recently, researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) have developed a high-throughput MS platform that enables in situ screening of fatty acid-producing strains. Mass spectrometry (MS) is a valuable analytical tool for high-throughput screening due to its speed, high resolution, and sensitivity. Recently, researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese ...

  • 06

    11 2023

    Structurally Editable Proximal Cofactor-like Module Helps to Construct Artificial Dual-center Peroxygenase

    A new study led by Prof. CONG Zhiqi from Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) has developed an unprecedented approach for assembling artificial metalloenzymes and substantially increases the catalytic promiscuity of P450 enzymes. Cytochrome P450 monooxygenases are widely involved in the synthesis and metabolism of endogenous and exogenous substances in living organisms. The catalytic efficiency of cytochrome P450 monooxygenase relies on the coenzyme NAD(P)H and reducing ch...

  • 27

    10 2023

    Newly Discovered Bacterial Transcription Mechanism May Inform Synthetic Biology Engineering

    Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) have discovered that the SigI are more distinct than previously understood — so much so that they require an entirely new classification group. Their findings, published in Nature Communications on Oct. 13, may help inform the design of gene regulation tools. Bacterial transcription is a production line of copying over genetic instructions from double stranded DNA to produce RNA, which is then used for the subsequent production of proteins that the bacterium needs at that moment. The line supervisors a...

  • 24

    10 2023

    Iodine Improves lithium Thionyl Chloride Battery Discharge Performance and Rechargeability

    Lithium thionyl chloride (Li-SOCl2) batteries use a liquid thionyl chloride (SOCl2) electrolyte to give the battery superior energy density and stability, long life and low levels of energy loss during storage. Despite these advantages, Li-SOCl2 batteries can only be used in devices requiring low rates of energy discharge and cannot be recharged. Incorporating molecular iodine (I2) into the SOCl2 battery electrolyte not only increases the rate of energy discharge but also allows the battery to be efficiently recharged, increasing the practicality of Li-SOCl2 batteries for routine energy storage. Lithium thionyl chloride (Li-SOCl2) batteries use a liquid thionyl chloride (SOCl2) electrolyte to give the battery superior energy density and stability, long life and low levels of energy loss during storage.
      Despite these advantages, Li-SOC...

  • 09

    10 2023

    Salt-Concentrated Hydrogel Electrolytes for Long-Life Rechargeable Batteries

    Recently, researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) have developed an unconventionally salt-concentrated hydrogel electrolyte reaching a salt fraction up to 44 mol% without phase separation, which essentially suppresses water-induced side reactions and thus enables practical long-cycling operation of aqueous sodium-ion batteries. Hydrogel electrolytes are promising in developing flexible and safe batteries, but the presence of large amounts of free solvent water makes battery chemistries constrained by parasitic H2 evolution and electrode dissolution.
      Recently, researc...