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Research Progress
  • 26

    07 2023

    Observation of Protein Conformational Dynamics in Live cells

    Recently, a research team from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) has investigated the protein loop conformational dynamics in Escherichia coli ( E.coli ) cells by Nuclear Magnetic Resonance (NMR) Spectroscopy. Protein dynamics through motions of loops, linkers, and hinges can generate distinctive conformations that are important for protein function.
      For example, protein folding, recognition, conformation, and enzyme catalysis are all related to the...

  • 20

    07 2023

    Bacterial Signaling Autoproteolysis Confirmed in C. thermocellum

    Transmembrane signaling involves sensing and communicating with the extracellular environment, which is of utmost importance when it comes to cell survival. Part of the transmembrane signaling is a process known as autoproteolysis, which is key in different functions of a cell such as signal transduction in eukaryotes and protease maturation in prokaryotes. In this process a peptide chain, which is a string of amino acids, is cleaved at a specific site by the peptide itself. This is typical of eukaryotes, though a defined, functional autoproteolytic event for transmembrane signal transduction has not been seen in bacteria until now. Transmembrane signaling involves sensing and communicating with the extracellular environment. Part of the transmembrane signaling is a process known as autoproteolysis, which is key in different functions of a cell.
      In this process a peptide ...

  • 20

    07 2023

    Bacterial Single-cell Whole Genome Sequencing Overhauled by Eengineered Polymerase

    Sequencing the genome of single cells has long been technically difficult and cursed by seemingly incorrigible bias in the gene amplification stage of the process, making it almost impossible to carry out research on rare cell types such as circulating tumor cells. A new process, however, radically reduces that bias, opening up whole new vistas of single-cell research. Sequencing the genome of single bacterial cells has long been technically difficult due to the seemingly incorrigible bias in the gene amplification stage of the process, making it hard to produce high-coverage genome sequence from precisely just ...

  • 29

    06 2023

    Novel Strategies to Accelerate the Application of High-Energy Lithium Metal Batteries

    Recently, a research team led by Prof. CUI Guanglei from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT), Chinese Academy of Sciences (CAS), has made significant progress in the field of high specific energy lithium metal batteries (LMBs). The development of LMBs with energy density exceeding 500 Wh kg-1 has garnered significant attention, especially in the special scenario applications. However, due to the strong reduction capability of Li metal anode, the parasitic side reactions ...

  • 26

    06 2023

    Researchers Succeed in Converting Carbon Dioxide into Glucose Utilizing Cyanobacteria

    a research team led by Prof. LU Xuefeng and Prof. LUAN Guodong from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT), Chinese Academy of Sciences (CAS), identified the key factors restricting the natural potentials of cyanobacteria for the directly converting carbon dioxide into glucose and constructed efficient glucose synthesizing photosynthetic cell factories. Glucose is the most abundant monosaccharide, serving as an essential energy source for cells and as an important feedstock for the biorefinery industry. The plant-biomass-sugar route dominates the current glucose supply, while it is influenced by ...

  • 20

    06 2023

    Antibacterial detergents reduce microbial exchange and malodor in textiles during laundry

    Although antibacterial detergents have been demonstrated to reduce malodor in textiles, their impact on microbial diversity during the laundry process and the subsequent effect on malodor in textiles have yet to be fully examined. Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) and Procter & Gamble have provided evidence to address this in a recent study. Although antibacterial detergents have been demonstrated to reduce malodor in textiles, their impact on microbial diversity during the laundry process and the subsequent effect on malodor in textiles have yet to be fully examined. Researchers from...