09
07 2021
In recent years, a research team led by Prof. CONG Zhiqi from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) have reported the highly efficient peroxygenase function of the DFSM-facilitated P450BM3-H2O2 system, but there is little research about the peroxidase function.
Enzyme catalysis is a promising green solution for producing pharmaceuticals, fine chemicals, and biofuels. However, exploring their catalytic promiscuity to expand and enhance the capabilities of enzymes remains challenging.
A research team l...
05
07 2021
The Catalytic Polymerization and Process group led by Prof. WANG Qinggang from Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT), Chinese Academy of Sciences (CAS) has developed a novel strategy, which is protonic acid and ionic liquid catalysis. The related research is published in Macromolecules. Synthetic rubber especially low-molecular-weight and high trans-1,4 polyisoprene liquid rubber have been widely applied. At present, cationic polymerization is the dominant way to prepare high trans-1,4 polyisoprene.However, it faces the challenge...
05
07 2021
The Metabolomics Group of Qingdao Institute of Bioenergy and Processes (QIBEBT), Chinese Academy of Sciences (CAS), has introduced an exogenous BGL into Clostridium thermocellum to construct two generations of CBS biocatalysts and achieved efficient cellulose hydrolysis and glucose production. Then, the researchers achieved high-level expression of BGL in C. thermocellum and constructed the third-generation CBS biocatalyst. Lignocellulosic biomass is considered as a great substitute for fossil resources for its advantages in carbon emission reduction. Because of the complex composition and recalcitrant structure of lignocellulose, efficient and low-cost lignocellulos...
17
06 2021
Microalgae are “simple” organisms of single cells, yet they pack a mighty potential punch when it comes to helping humanity achieve carbon neutrality, according to researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT), of the Chinese Academy of Sciences (CAS). The organisms can convert greenhouse gases such as carbon dioxide into energy, producing materials less harmful and more useful for the planet. Microalgae are "simple" organisms of single cells, yet they pack a mighty potential punch when it comes to helping humanity achieve carbon neutrality, according to researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBE...
07
06 2021
An international team of researchers has proposed a new approach via combining protein engineering and dual-functional small molecule (DFSM) regulation of a unique non-natural P450BM3 peroxygenase to achieve excellent H2O2-dependent (R)-enantioselective epoxidation of styrene and its derivatives.
They published their study on Chemical Science, the flagship journal of Royal Society of Chemistry.
Optically-pure styrene oxides are useful building blocks for synthesizing chiral organic compounds and functional polymers. The asymmetric epoxidation of styrenes is one direct way to prepare optically-pure styrene oxides.
However, highly (R)-...
27
05 2021
Researchers from the Single-Cell Center at the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) have developed a technique to sort and sequence the genome of bacteria in soil one bacterial cell at a time, while also identifying what its function is in the soil environment. Their study was published in the journal mSystems on May 27. A new, extremely precise technique has been developed that allows the identification of the metabolic function and genome of soil bacteria one bacterial cell at a time instead of having to analyze millions all at once. The process should permit 'm...
