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Research Progress
  • 18

    01 2021

    Single-cell Test Can Reveal Precisely How Drugs Kill Cancer Cells

    Cancer cells are smart when it comes to anti-cancer drugs, evolving and becoming resistant to even the strongest chemotherapies over time. To combat this evasive behavior, researchers have developed a method to see, at the atomic level, how pharmaceuticals induce cancer cell death and how cancer cells adapt. The research, conducted at the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT), Chinese Academy of Sciences (CAS), was published on Jan. 12 in Analytical Chemistry, a journal of the American Chemical Society. Cancer cells are smart when it comes to anti-cancer drugs, evolving and becoming resistant to even the strongest chemotherapies over time. To combat this evasive behavior, researchers have developed a method named D2O-probed CANcer Susceptibility ...

  • 25

    12 2020

    Cellulose Nanofibril-based Encapsulation Structure Achieve Controlled Drug Release

    The Metabolomics Group led by Prof. CUI Qiu from QIBEBT collaborated with the researchers from Tianjin University of Science & Technology constructed a new drug loading system with an encapsulation structure for the controllable drug release, based on their previous works Intelligent hydrogels with multifunction such as sustained drug release abilities with low burst release, antibacterial properties, and biocompatibility are highly desirable in biomaterials fields, particularly for the cellulose-based drug carrier...

  • 11

    12 2020

    Scientists Fabricate Versatile Catalyst for Polyesters Synthesis and Degradation

    Recently, a research group led by Prof. WANG Qinggang, from the Qingdao Institute of Bioenergy and Bioprocess Technology of the Chinese Academy of Sciences, reported a new catalytic approach, which affording controlled polymerizations of lactones and efficient depolymerizations of polyesters. White pollution from discarded plastic waste is one of the most urgent environmental problems facing human beings. With the rapid development of science and technology and the increasing awareness of environmental protection, degradable green func...

  • 26

    10 2020

    Scientists Established NanDeSyn Database to Support International Cooperation on Industrial Microalgae

    To promote resource sharing and research cooperation for the synthetic biology and molecular breeding of industrial oil-producing microalgae, an international team led by Single-Cell Center (SCC), Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT), Chinese Academy of Sciences (CAS) have released the "NanDeSyn Database” (http://www.nandesyn.org). This work was recently published in The Plant Journal. Industrial oil-producing microalgae can use light energy to convert carbon dioxide and water into oils on a large scale. Therefore, it is a potential solution for the sustainable supply of food, nutrition and fuel for human society.
      To promote...

  • 24

    10 2020

    Discovery of pH-dependent 'switch' in Interaction between Pair of Protein Molecules

    All biological processes are in some way pH-dependent. Our human bodies, and those of other organisms, need to maintain specific -- and constant -- pH regulation in order to function. Changes in pH can have serious biological consequences or, as researchers at the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT), Chinese Academy of Sciences (CAS) found, serious benefits.The findings are published Oct. 23 in the journal Science Advances. All biological processes are in some way pH-dependent. Our human bodies, and those of other organisms, need to maintain specific -- and constant -- pH regulation in order to function. Changes in pH can have serious biological consequences or, as r...

  • 20

    10 2020

    Scientists Propose Novel Selective Transfer Hydrogenation Catalysts with Improved Stability

    Recently, a research team led by Prof. WANG Guanghui from Qingdao institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS), in collaboration with Prof. ZHANG Wenhua from University of Science and Technology of China (USTC), reported a new Ni3Al1-oxide hollow nanosphere (h-Ni3Al1-800) derived from Ni3Al1 layered double hydroxide grafted on hollow polymer spheres (HPS@Ni3Al1-LDH) by calcination at 800℃ under air, where the selectivities towards unsaturated alcohols are always higher than 99 % at almost full conversions. Alcohols are important compounds widely used in the food, fragrance, pharmaceutical and bulk/fine chemical industries. α,β-unsaturated alcohols is a kind of alcohol that can be produced via the hydrogenation of α,β-unsaturated aldehydes.
      H...