Biomacromolecules, such as DNA, protein, and carbohydrate etc., can form well-organized, high ordered nanostructures, which plays an important role in the functionalization of organisms. The construction of biobased materials by taking advantage of the well-organized hierarchical nanostructures and the biocompatibility of biomolecules has been attracting much attention. Prof. WAN Xiaobo's group has synthesized biomimetic oligopeptides which can form b-sheet structures and further investigated the peptide-directed self-assembly of functional molecules, especially the conjugated semiconductors. Biomacromolecules, such as deoxyribonucleic acid (DNA), protein, and carbohydrate etc., can form well-organized, high ordered nanostructures, which plays an important role in the functionalization of organisms. The construction of biobased materia...
Microalgae are able to convert solar energy and carbon dioxide to energy storage compounds such as starch and lipids to produce food and biofuels. Therefore screening and engineering strains for higher starch productivity have been of great interest. Prof. XU Jian from QIBEBT has now established a novel approach for quantitation of starch in live, unicellular microalgae at single-cell resolution. Microalgae are able to convert solar energy and carbon dioxide to energy storage compounds such as starch and lipids to produce food and biofuels. Therefore screening and engineering strains for higher starch productivity have been of great intere...
The peptide microarray received much attention from all research fields due to its excellent properties. However, to date, the performance of peptide microarray has been limited by the composition, direction and density of peptide ligands used. The Laboratory for Biosensing at QIBEBT respond to the challenges by taking the cellulytic enzyme endoglucanase I as a model for selection of its specific peptide ligands from the f8/8 landscape library. The peptide microarray received much attention from all research fields due to its excellent properties, such as small size, affordability, convenience, high-throughput, automation and speediness. However, to date, the performance of peptide micro...
Clostridium thermocellum is known as the most efficient cellulose-degrader in nature. However, due largely to lack of efficient methods for genetic manipulation of C. thermocellum, in vivo function of its cellulosome system is rarely studied. QIBEBT scientists are working towards the study on C. thermocellum and its cellulosome for long term, and has analyzed the intracellular functions of all scaffoldin proteins in C. thermocellum using a newly developed thermotargetron system. Clostridium thermocellum is known as the most efficient cellulose-degrader in nature. However, due largely to lack of efficient methods for genetic manipulation of C. thermocellum, in vivo function of its cellulosome system is rarely studied. Meta...
Sterols are vital components of all eukaryotic cells. QIBEBT and UWA have now reported the unique sterol biosynthetic pathway and revealed co-regulation of sterol production and fatty acid synthesis in an oleaginous microalga. Sterols are vital components of all eukaryotic cells. However, little is known about the roles, biosynthesis, and regulation of sterols in microalgae. A joint research team led by Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese A...
Poplar has many advantages as a tree model for woody plant biology. However, the molecular mechanisms underlying secondary wall formation remain elusive in poplar. QIBEBT scientists have firstly reported the molecular mechanism of PdC3H17 and PdC3H18 regulating secondary wall formation in poplar and Arabidopsis. Poplar has many advantages as a tree model for woody plant biology. These include rapid and perennial growth, moderate genome size, biomass-related traits and relatively easy transformation. However, the molecular mechanisms underlying secondary w...