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Research Progress
  • 15

    01 2018

    How does the thermostable enzyme bind substrate tightly at elevated temperature?

    Temperature is one of the most important factors for evolution. As the temperature increases, the catalytic activity of the enzyme increases correspondingly, but at the same time, the affinity between the enzyme and the substrate decreases. It has been proved that metal ions enhance the activity, stability and substrate affinity of metal enzymes. However, the role of metal ions-binding amino acids in thermophilic adaptation is not clear. Recently, a research team led by Prof. LI Fuli from Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT), Chinese Academy of Sciences (CAS), unraveled the function of metal ions-binding amino acids in improving substrate affinity. Temperature is one of the most important factors for evolution. As the temperature increases, the catalytic activity of the enzyme increases correspondingly, but at the same time, the affinity between the enzyme and the substrate decreases. It ha...

  • 18

    12 2017

    Best-ever Performance Magnesium Sulfur Battery System Born in Qingdao

    As regards the demand for energy storage batteries, higher energy density and safer property has been the imperative target with the rapid market expansion of electric vehicles and grid-scale storage systems. Among various new battery technologies, rechargeable Mg battery has attracted increasing attention from researchers. Mg anode inherently possesses incomparable superiorities which are high safety, high volumetric capacity, earth-abundant element (the fifth most abundant in the earth crust) and low cost (about 30 times cheaper than Li). Nevertheless, the lack of compatible electrolytes and suitable cathodes has restricted the further development of rechargeable Mg battery. As regards the demand for energy storage batteries, higher energy density and safer property have been the imperative target with the rapid market expansion of electric vehicles and grid-scale storage systems. Among various new battery technologie...

  • 04

    12 2017

    Scientists Developed Raman-Activated Droplet Sorting System for Single-Cell Screening

    Single-cells are the basic unit of cellular life function and evolution on earth .Due to its label-free and non-invasive features , Raman-activated cell sorting ( RACS ) , which sorts cells based on their Single-cell Raman Spectrum ( SCRS ) , has attracted increasing interest .Chinese Academy of Sciences ( CAS ) developed a novel Raman-activated single-cell Droplet Sorting ( RADS ) technique , which featured the highest sorting throughput among the existing RACS . This new work was published on Analytical Chemistry . Single-cells are the basic unit of cellular life function and evolution on earth. Accurate and high-throughput sorting of single-cells are key tools for mechanistic dissection of functional heterogeneity among cells and probing yet-to-be-cultured ...

  • 29

    11 2017

    Scientists Produce Designer Oils in Industrial Microalgae

    Due to the high photosynthetic growth potential and rich oil content , many oil-rich algae have aroused people ' s interest .They could be employed as feedstock for scalable production of biofuels and biomaterials from carbon dioxide .As a main form of energy storage in microalgal cells , triacylglycerol ( TAG ) molecule consists of three fatty acids ( FAs ) moieties .The diversity and relative abundance of these FAs are the most important factors to determine the quality , utilization and economic value of algal oil . Due to the high photosynthetic growth potential and rich oil content, many oil-rich algae have aroused people's interest. They could be employed as feedstock for scalable production of biofuels and biomaterials from carbon dioxide. As a main form ...

  • 29

    11 2017

    Two Modification Hydrolases “Speed-Up” Biomass Utilization

    Biomass is the most abundant bio-resource on earth .Its utilization enrolls in the central step of “ Carbon Cycle ” in nature , and now offers the renewable materials for modern industry .After billions years evolution , plant cell walls formed a natural degradation – resistant barriers .A research group in Qingdao Institute of Bioenergy and Bioprocess Technology ( QIBEBT ) , Chinese Academy of Sciences ( CAS ) , reported two modification glucoside hydrolases , which were hyperthermophilic-tolerant , to accelerate biomass degradation . Biomass is the most abundant bio-resource on earth. Its utilization enrolls in the central step of “Carbon Cycle” in nature, and now offers the renewable materials for modern industry. After billions years evolution, plant cell walls formed a na...

  • 28

    11 2017

    New Insights about Relation between Glycogen and Sucrose Syntheses in Cyanobacteria

    Cyanobacteria , former named blue-green algae .Have been attracting increasing research interest for the production of biofuels and biochemicals in recent years due to their capability to convert atmosphere CO2 and light energy to carbohydrates by oxygenic photosynthesis .Many freshwater or marine species of cyanobacteria naturally synthesize and accumulate sucrose when stressed by salt ( NaCl ) , which provides novel possibilities for obtaining sugar feedstock by engineering of cyanobacteria . Cyanobacteria, former named blue-green algae, have been attracting increasing research interest for the production of biofuels and biochemicals in recent years due to their capability to convert atmosphere CO2 and light energy to carbohydrates by ...