Research Groups
| Group Name | Leader |
| Genome Engineering Group | XU Jian |
| Tool Enzyme Group | XIN Yi |
| Microfluidics Systems Group | MA Bo |
| Single-Cell Instrument Development Group | MA Bo |
| Bioinformatics Group | - |
| Single-Cell Application Demonstration Group | JI Yuetong & ZHU Pengfei |
| Advanced Bio-imaging Group | SHEN Wei |
| Admin Team | HAN Bo |
Research Interest
Raman-activated Cell Sorting (RACS), single-cell sequencing, single-cell metabolic phenome, anmicrobial susceptibility test (AST), microalgal synthetic biology, carbon neutral, carbon dioxide fixation, human microbiome and health.
Research Fields
1. Single-cell analysis and instrument development
2. Microalgal synthetic biology for carbon dioxide fixation and biofuels
3. Human microbiota and health
2. Microalgal synthetic biology for carbon dioxide fixation and biofuels
3. Human microbiota and health
Representative Research
Single-cell analysis and instrument development
1. Single-cell test can reveal precisely how drugs kill cancer cells
2. Spontaneous droplet generation via surface wetting
3. Scientists Introduce FlowRACS for High-throughput Discovery of Enzymes
4. Function-based sequencing technique permits analysis of just a single bacteria cell
5. Researchers Improve Method That Links Genome to Function for Environmental Single-cells
6. Chinese Scientists Develop Novel Instrument for Rapid Profiling of Antimicrobial Resistance
7. Chinese Scientists Develop World’s First Instrument System for Raman-activated Cell Sorting and Sequencing
8. Raman-activated cell sorting and metagenomic sequencing revealing carbon-fixing bacteria in the ocean
9. Label-free, Simultaneous Quantification of Starch, Protein and Triacylglycerol in Single Microalgal Cells
10. Raman-Activated Droplet Sorting (RADS) for Label-Free High-Throughput Screening of Microalgal Single-Cells
11. Metabolic-activity based assessment of antimicrobial effects by D2O-labeled Single-Cell Raman Microspectroscopy
1. Single-cell test can reveal precisely how drugs kill cancer cells
2. Spontaneous droplet generation via surface wetting
3. Scientists Introduce FlowRACS for High-throughput Discovery of Enzymes
4. Function-based sequencing technique permits analysis of just a single bacteria cell
5. Researchers Improve Method That Links Genome to Function for Environmental Single-cells
6. Chinese Scientists Develop Novel Instrument for Rapid Profiling of Antimicrobial Resistance
7. Chinese Scientists Develop World’s First Instrument System for Raman-activated Cell Sorting and Sequencing
8. Raman-activated cell sorting and metagenomic sequencing revealing carbon-fixing bacteria in the ocean
9. Label-free, Simultaneous Quantification of Starch, Protein and Triacylglycerol in Single Microalgal Cells
10. Raman-Activated Droplet Sorting (RADS) for Label-Free High-Throughput Screening of Microalgal Single-Cells
11. Metabolic-activity based assessment of antimicrobial effects by D2O-labeled Single-Cell Raman Microspectroscopy
12. Development of a facile droplet-based single-cell isolation platform for cultivation and genomic analysis in microorganisms
13. Reverse and multiple stable isotope probing to study bacterial metabolism and interactions at the single cell level
14. Label-free, rapid and quantitative phenotyping of stress response in E. coli via ramanome
15. Raman-activated Cell Sorting based on dielectrophoretic single-cell trap and release
16. Researchers Develops Novel Approach for Quantitation of Starch in Live, Unicellular Microalgae
17. Researchers Develops Novel Approach for Label-free Measurement of Triacylglycerol Content of Live Single Cells
18. Raman-Activated Cell Sorting for Single Cell Isolation
13. Reverse and multiple stable isotope probing to study bacterial metabolism and interactions at the single cell level
14. Label-free, rapid and quantitative phenotyping of stress response in E. coli via ramanome
15. Raman-activated Cell Sorting based on dielectrophoretic single-cell trap and release
16. Researchers Develops Novel Approach for Quantitation of Starch in Live, Unicellular Microalgae
17. Researchers Develops Novel Approach for Label-free Measurement of Triacylglycerol Content of Live Single Cells
18. Raman-Activated Cell Sorting for Single Cell Isolation
Microalgal synthetic biology for carbon dioxide fixation and biofuels
1. Scientists program microalgae's 'oil factory' to produce various oils
2. Genome scalpel invented for industrial microalgae to efficiently turn CO2 into biofuel
3. Scientists establish NanDeSyn Database to support international cooperation on industrial microalgae
4. Integration of proteome and transcriptome refines key molecular processes underlying oil production in Nannochloropsis oceanica
5. Highly Efficient, Low-cost Method Developed to Reduce DNA Errors
6. Transcriptomic and proteomic responses to very low CO2 suggest multiple carbon concentrating mechanisms in Nannochloropsis oceanica
7. Turn Back the Clock of Evolution: CAS Scientists Developed High-CO2-tolerant Super Oleaginous Microalgae
8. Scientists Produce “Designer Triacylglycerols” in Industrial Microalgae
9. QIBEBT Generated Super-microalga for CO2 Fixation
10. RNAi-based targeted gene-knockdown in the model oleaginous microalgae Nannochloropsis oceanica
11. Genome editing of model oleaginous microalgae Nannochloropsis spp. by CRISPR/Cas9
12. Researchers Reveals Regulatory Mechanism of Cellulosome Stoichiometry
13. Researchers Advocate for Exploiting Power of Phytohormones in Microalgal Biotechnology
14. Molecular mechanisms of photosynthetic carbon partitioning were unveiled
15. Researchers Unveiled Genome-wide Transcriptional Regulation Network of Oleaginous Microalgae Nannochloropsis
16. Researchers Reveals Biosynthetic and Regulatory Mechanisms of Steroids in Microalgae
17. Researchers Reveals Molecular Mechanisms of Oil Synthesis in Microalgae
18. Researchers reveals the genetic foundation and evolutionary origin of oleaginous traits in microalgae
19. Researchers proposes a new strategy for intragenus phylotyping of microalgae
20. Dissecting and engineering metabolic and regulatory networks of thermophilic bacteria for biofuel production
21. Microevolution from shock to adaptation revealed strategies improving ethanol tolerance and production in Thermoanaerobacter
2. Genome scalpel invented for industrial microalgae to efficiently turn CO2 into biofuel
3. Scientists establish NanDeSyn Database to support international cooperation on industrial microalgae
4. Integration of proteome and transcriptome refines key molecular processes underlying oil production in Nannochloropsis oceanica
5. Highly Efficient, Low-cost Method Developed to Reduce DNA Errors
6. Transcriptomic and proteomic responses to very low CO2 suggest multiple carbon concentrating mechanisms in Nannochloropsis oceanica
7. Turn Back the Clock of Evolution: CAS Scientists Developed High-CO2-tolerant Super Oleaginous Microalgae
8. Scientists Produce “Designer Triacylglycerols” in Industrial Microalgae
9. QIBEBT Generated Super-microalga for CO2 Fixation
10. RNAi-based targeted gene-knockdown in the model oleaginous microalgae Nannochloropsis oceanica
11. Genome editing of model oleaginous microalgae Nannochloropsis spp. by CRISPR/Cas9
12. Researchers Reveals Regulatory Mechanism of Cellulosome Stoichiometry
13. Researchers Advocate for Exploiting Power of Phytohormones in Microalgal Biotechnology
14. Molecular mechanisms of photosynthetic carbon partitioning were unveiled
15. Researchers Unveiled Genome-wide Transcriptional Regulation Network of Oleaginous Microalgae Nannochloropsis
16. Researchers Reveals Biosynthetic and Regulatory Mechanisms of Steroids in Microalgae
17. Researchers Reveals Molecular Mechanisms of Oil Synthesis in Microalgae
18. Researchers reveals the genetic foundation and evolutionary origin of oleaginous traits in microalgae
19. Researchers proposes a new strategy for intragenus phylotyping of microalgae
20. Dissecting and engineering metabolic and regulatory networks of thermophilic bacteria for biofuel production
21. Microevolution from shock to adaptation revealed strategies improving ethanol tolerance and production in Thermoanaerobacter
22. Structure and regulation of the cellulose degradome in Clostridium cellulolyt
Human microbiota and health
1. New Study Shows 24-72 Hours of Poor Oral Hygiene Impacts Oral Health
2. Microbiome Search Engine 2 helps researchers explore microbiome space
3. Meta-Apo supports cheaper, quicker microbiome functional assessment
4. Microbiome Search Engine Can Increase Efficiency in Disease Detection and Diagnosis
5. Mining metagenomics: A faster and more efficient method to compare metagenomes
6. Scientists Use Skin’s Microbiome to Develop Health Index for Children with Eczema
7. Scientists Develop Microbiome Search Engine to Assess Microbiome Novelty and Impact
8. CAS (Single-Cell Center)-SYSU Joint Team Developed Microbiota-Based Approach for Predicting Early Childhood Caries
9. Metagenomics Used in Biological Ingredient Analysis of Traditional Chinese Medicine Preparation
10. Oral Microbiota Predict Gingivitis Severity and Susceptibility: Single-Cell Center of QIBEBT and P&G Collaborate on Oral Microbiome Research
11. Bioinformatics Group of Single-Cell Center Proposed High-Performance Computational Method to Significantly Accelerate Large-scale Microbial Community Analysis
12. Bioinformatics Group of our center and NVIDIA co-Established a New CUDA Research Centre
Contact
xujian@qibebt.ac.cn
